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St. John's Wort

"St. John's wort (Hypericum perforatum) is a plant with yellow flowers that people in European countries have used for centuries to treat mild to moderate depression." - WebMD®

"Overall, the scientific evidence supports the effectiveness of St. John's wort in mild-to-moderate major depression. The evidence in severe major depression remains unclear." - Mayo Clinic

See below for information on -
Overview   Possible Benefits   Treatment for Depression
Cautions   Manufacturers' Info
Up-to-the-Minute News



Brand Description Price Qty
Nature's Way St. John's Wort, 350 MG, 100 capsules 8.50
Nature's Way Perika® St. John's Wort, 300 mg, 60 tablets 13.00
Usually ships in one business day.



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Supplement Facts

Nature's Way Capsules
Suggested Usage: Take 2 capsules twice daily, preferably with food. For maximum benefit use for at least two months.
Amount Per Servingmg
St. John's Wort (stem, leaf, flower)700
Total carbohydrate: 1 g.
Other Ingredients: gelatin, cellulose.
Twinlab L-Carnitine Capsules contain no synthetic D-Carnitine or DL-Carnitine. D-Carnitine and DL-Carnitine are less effective than L-Carnitine. D-Carnitine and DL-Carnitine are not recommended because of their adverse physical side effects.

Well tolerated by most highly allergic individuals. No tablet binders, coatings or colorings.
Nature's Way Perika® Tablets
Suggested Usage: Take one (1) Perika® tablet with water three times daily at mealtimes. This dosage has been confirmed in recent clinical research. Benefits are best realized after 2-4 weeks of regular usage.
Amount Per Servingmg
St. John’s Wort (stem, leaf, flower)300
Vitamin C (ascorbic acid)4
Patented standardized extract WS® 5572 containing a minimum level of 3% hyperforin.
Other Ingredients: cellulose, modified cellulose, starch, silica, magnesium stearate, titanium dioxide.
Twinlab Mega L-Carnitine Tablets contain only L-CARNIPURE® L-Carnitine, and does not contain any synthetic D-Carnitine or DL-Carnitine. D-Carnitine and DL-Carnitine are less effective than L-Carnitine. D-Carnitine and DL-Carnitine are not recommended because of their adverse physical side effects.

The following are excerpts from
U.S. NCCAM National Institutes of Health -

Overview

The name St. John's wort apparently refers to John the Baptist, as the plant blooms around the time of the feast of St. John the Baptist in late June. The flowering tops of St. John's wort are used to prepare teas and tablets containing concentrated extracts.

Possible Benefits

Possible benefits [include] -
  • St. John's wort has been used for centuries to treat mental disorders and nerve pain.
  • St. John's wort has also been used as a sedative and a treatment for malaria, as well as a balm for wounds, burns, and insect bites.
  • Today, St. John's wort is used by some for depression, anxiety, and/or sleep disorders.
As a Treatment for Depression

Scientific evidence regarding the effectiveness of St. John's wort for depression is inconsistent. An analysis of the results of 37 clinical trials concluded that St. John's wort may have only minimal beneficial effects on major depression. However, the analysis also found that St. John's wort may benefit people with minor depression; these benefits may be similar to those from standard antidepressants. Overall, St. John's wort appeared to produce fewer side effects than some standard antidepressants (emphasis added).

Cautions

St. John's wort may cause increased sensitivity to sunlight. Other side effects can include anxiety, dry mouth, dizziness, gastrointestinal symptoms, fatigue, headache, or sexual dysfunction. Research shows that St. John's wort interacts with some drugs. The herb affects the way the body processes or breaks down many drugs; in some cases, it may speed or slow a drug's breakdown. Drugs that can be affected include:
  • Antidepressants
  • Birth control pills
  • Cyclosporine, which prevents the body from rejecting transplanted organs
  • Digoxin, which strengthens heart muscle contractions
  • Indinavir and possibly other drugs used to control HIV infection
  • Irinotecan and possibly other drugs used to treat cancer
  • Warfarin and related anticoagulants
  • When combined with certain antidepressants, St. John's wort may increase side effects such as nausea, anxiety, headache, and confusion.
"Serotonin syndrome can occur when you take certain combinations of prescription medications [including some medications for depression or migraines] that affect serotonin levels in your body. ... Serotonin syndrome can also occur if you take SSRIs with other drugs or supplements that affect serotonin levels, such as St. John's wort. If not treated quickly, serotonin syndrome can become life-threatening." - Mayo Clinic

Manufacturers' Info from the Bottle Labels

From the Nature's Way Capsules label - St. John’s Wort (Hypericum perforatum) promotes a positive mood. It is native to Europe, North Africa, and western Asia.

From the Nature's Way Perika® Tablets label - Hyperforin: The proven "mood enhancing" active [ingredient] in St. John’s Wort. New clinical research reveals hyperforin-rich Perika® to be more effective in promoting a positive mood than low hyperforin St. John’s Wort. In fact, 15% more users reported "much or very much improved" emotional status by using Perika® in comparison to other St. John’s Wort. Perika’s HyperiSure® Difference: Hyperforin is rather unstable and can lose potency over time. However, using the patented HyperiSure® System technology, Perika® contains a guaranteed level of hyperforin to deliver clinically proven effectiveness.

Up-to-the-Minute News on St. John's Wort
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The content presented in this website is for informational purposes only. Before taking this or any other health supplement or therapy, consult your healthcare professional. Even mild supplements can have varying effects on individuals, and can conflict with your existing medications and diet. See additional information.

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